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Astaxanthin Research

Astaxanthin (pronounced "asta-ZAN-thin") is a naturally-occurring chemical compound found in algae, shellfish and salmon. For humans, astaxanthin is a powerful antioxidant with broad health implications.

Aids in the Fight Against Fatigue

Astaxanthin provides excellent recovery from exercise. Just like salmon making the brave upstream swim, astaxanthin can help athletes put forth their best effort. Pure, natural astaxanthin has been showed to be beneficial for recovery of muscles, better endurance, enhanced strength and improved energy levels.

Aoi, et al, 2003. Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice. Antioxid Redox Signal. 2003 Feb;5(1):139-44.

Curt L. Malmsten and Åke Lignell. Dietary Supplementation with Astaxanthin-Rich Algal Meal Improves Strength Endurance. A Double Blind Placebo Controlled Study on Male Students. Carotenoid Science, Vol.13, 2008 ISSN 1880-5671.

Aoi W, Naito Y, Takanami Y, Ishii T, Kawai Y, Akagiri S, Kato Y, Osawa T, Yoshikawa T. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochem Biophys Res Commun. 2008 Feb 22;366(4):892-7. Epub 2007 Dec 17.

Ikeuchi M, Koyama T, Takahashi J, Yazawa K. Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biol Pharm Bull. 2006 Oct;29(10):2106-10.

Promotes Eye Health

Astaxanthin has the unique ability to cross through barriers and reach the retina. Well-designed positive human clinical trials show that astaxanthin supports eye health.

Iwasaki Tsuneto, Tahara Akihiko. Effects of Astaxanthin on Eyestrain Induced by Accommodative Dysfunction. Journal of the Eye VOL.23;NO.6;829-834(2006)

Nagaki Y., Hayasaka S., Yamada T., Hayasaka Y., Sanada M., Uonomi T. Effects of Astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines 2002: 19 (5), 170 - 173.

Nagaki Yasunori et al. The Effect of Astaxanthin on Retinal Capillary Blood Flow in Normal Volunteers. Journal of Clinical Therapeutics & Medicines Vol.21;No.5;537-542(2005)

Sun Z, Liu J, Zeng X, Huangfu J, Jiang Y, Wang M, Chen F. Protective actions of microalgae against endogenous and exogenous advanced glycation endproducts (AGEs) in human retinal pigment epithelial cells. Food Funct. 2011 May;2(5):251-8. doi: 10.1039/c1fo10021a. Epub 2011 Apr 21. PubMed PMID: 21779563.

Liao JH, Chen CS, Maher TJ, Liu CY, Lin MH, Wu TH, Wu SH. Astaxanthin interacts with selenite and attenuates selenite-induced cataractogenesis. Chem Res Toxicol. 2009 Mar 16;22(3):518-25. doi: 10.1021/tx800378z. PubMed PMID: 19193053.

Helps Relieve Pain and Inflammation

Astaxanthin is a potent anti-inflammatory and pain reliever, blocking different chemicals in your body that make you shout "ouch!" More than that, astaxanthin reduces the inflammatory compounds that drive many chronic diseases.

Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM. Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation. Mol Cells. 2003 Aug 31;16(1):97-105. PubMed PMID: 14503852.

Pearson, Thomas; Mensah, George, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association.2003 Jan 28; 107(3) :499-511.

Gene A. Spiller, PhD, Antonella Dewell, MS, RD, Sally Chaves, RN, Zaga Rakidzich. Effect of daily use natural astaxanthin on C-reactive protein. Health Research & Studies Center, Los Altos, CA. Study Report, January, 2006.

Beautiful Skin

Astaxanthin has been shown to protect the body's largest organ, the skin. The studies are clear and consistent and show excellent results for helping with skin moisture levels, fine lines, smoothness, elasticity, freckles and spots.

Yamashita, E. Beauty From Within: A Synergistic Combination Of Astaxanthin And Tocotrienol For Beauty Supplements (2002) Cosmetic Benefit of Dietary Supplements Containing Astaxanthin and Tocotrienol on Human Skin. Food Style 21 6(6):112-17.

A novel micronutrient supplement in skin aging: a randomized placebo-controlled double-blind study. Journal of Cosmetic Dermatology Volume 4 Page 277 - December 2005

Suganuma K, Nakajima H, Ohtsuki M, Imokawa G. Astaxanthin attenuates the UVA-induced up-regulation of matrix- metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. J Dermatol Sci. 2010 May;58(2):136-42. Epub 2010 Feb 18.

Arakane Kumi. Effect of Antioxidant to Inhibit UV-Induced Wrinkles. Journal of Japanese Cosmetic Science Society Vol. 27;No.4; 298-303(2003).

Powerful Antioxidant

Natural astaxanthin is an incredibly powerful antioxidant. A 2007 study analyzed several popular antioxidants and their antioxidant power. This study found astaxanthin was 6,000 times stronger than vitamin C, 800 times stronger than CoQ10, 550 times stronger than green tea catechins and 75 times stronger than alpha lipoic acid.

Nishida Y. et. al, Quenching Activities of Common Hydrophilic and Lipophilic Antioxidants against Singlet Oxygen Using Chemiluminescence Detection System. Carotenoid Science 11:16-20 (2007)

Iwamoto T, et al. Inhibition of low-density lipoprotein oxidation by astaxanthin. J Atherosc Thromb 2000;7:216-22.

Camera E, Mastrofrancesco A, Fabbri C, Daubrawa F, Picardo M, Sies H, Stahl W. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress- responsive enzymes. Exp Dermatol. 2009 Mar;18(3):222-31. Epub 2008 Sep

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